Antibiotics

Product 100 mL $30

Amphotericin B (FUNGIZONE®) Solution 250µg/mL
400-104

Amphotericin B is one of the earliest compounds designed to kill fungi. It was developed to help treat fungal infections intravenously. It has since been found to help eliminate fungal contamination in cell cultures as well. Low doses (0.5 to 2.0 ug/mL) are recommended as it is toxic to other eukaryotic cells at higher concentrations.

Final concentration of Amphotericin B is undiluted, 250ug/mL.

Sterile-filtered
Ships on dry ice. Store frozen at -20 to -10°C
FUNGIZONE® is a registered trademark of E.R. Squibb

CAS Number 1397-89-3

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Product 25 g $140100 g $360

Ampicillin Powder
400-130P

This beta-lactam antibiotic is an aminopenicillin. Like penicillin, it inhibits bacterial cell wall synthesis by preventing peptidoglycan cross-linking and murein assembly. The presence of an amino group confers greater efficacy against Gram-negative bacteria as compared to penicillin. Ampicillin is commonly used in molecular biology to assay for gene uptake (e.g., plasmid vectors carrying the ampicillin resistance gene).

Ships on ice. Store refrigerated at 2 to 8°C

CAS Number 7177-48-2

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Product 100 mL $19

Antibiotic:Antimycotic Solution
400-101

Gemini’s antibiotic:antimycotic (anti:anti) solution is for general prophylactic use. Dilute 100-fold for use in media (10mL/L). This product is useful as a broad spectrum anti-bacterial and anti-fungal agent. This product is not recommended for cultures with established fungal contamination due to the low concentration of amphotericin B. See Amphotericin B for elimination of fungal contamination in culture.

10,000 units/mL penicillin G, 10mg/mL streptomycin sulfate, 25µg/mL amphotericin B with 8.5 g/L NaCI

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Product 50 mg $163100 mg $315

Blasticidin S HCL Powder
400-165P

Blasticidin, from Streptomyces griseochromogenes, is an antibiotic commonly used in gene selection.

Blasticidin is active against both prokaryotic and eukaryotic. Resistance to blasticidin is conferred by the blasticidin resistance gene from bacillus cereus (bsr). Bsr codes for blasticidin deaminase.

Ships on ice. Store refrigerated at 2 to 8°C.

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Product 2 g $925 g $153

Carbenicillin Powder
400-105P

Carbenicillin is a third-generation analog of penicillin. Like penicillin, it inhibits bacterial cell wall synthesis by preventing peptidoglycan cross-linking and murein assembly. It shows greater efficacy against Gram-negative bacteria as compared to penicillin. It may be useful against some species of Pseudomonas and Serratia, but has not been generally used in mammalian cell cultures. However, plant cell culturists have found this to be a useful prophylactic agent against many organisms, such as Agrobacterium. Recommended concentration in cell culture is 100 mg/L.

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Chloramphenicol Powder
400-951P

Chloramphenicol, also known as chlornitromycin, is a broad-spectrum, bacteriostatic antibiotic derived from Streptomyces venezuelae. It is effective against several gram-positive and gram-negative bacteria and commonly used in researching protein synthesis, ophthalmic and veterinary purposes. Recommended concentration in cell culture is 5 ug/mL.

Ships on dry ice. Store desiccated at -20°C.

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Elastase
400-146P

Lyophilized from Porcine Pancreas and is used for Tissue Dissociation and Cell Isolation.

Store frozen at -20°C

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Product 1 g $1085 g $270

G418 Sulfate Powder
400-111P

G418 sulfate, an aminoglycoside antibiotic, is related to gentamicin. G418 is toxic to both prokaryotic and eukaryotic cells. It is used primarily for the selection of eukaryotic expression vectors bearing the related resistance genes. Recommended concentration varies by cell type; in mammalian cells, 400 mg/L is recommended for initial selection, and then reduced to 200 mg/L for culture maintenance.

Ships on blue ice. Store refrigerated at 2 to 8°C
G418 is also known by the trademark Geneticin®, as registered to Invitrogen Corporation. 

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Product 20 mL $97

G418 Sulfate Solution (50 mg/mL)
400-113

G418 sulfate, an aminoglycoside antibiotic, is related to gentamicin. G418 is toxic to both prokaryotic and eukaryotic cells. It is used primarily for the selection of eukaryotic expression vectors bearing the related resistance genes. Recommended concentration varies by cell type.

Sterile-filtered
Ships on ice. Store refrigerated at 2 to 8°C
G418 is also known by the trademark Geneticin®, as registered to Invitrogen Corporation.

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Product 10 g $153

Gentamicin Sulfate Powder
400-100P

Gentamicin kills Gram-negative and Gram-positive bacteria, and mycoplasma. It works by binding to microbial ribosomes and preventing the initiation of protein synthesis. Gentamicin is very stable in solution and lasts many days in culture. It is generally more effective than streptomycin. This product should be used with caution, as high concentrations can retard cell growth. Recommended concentration in cell culture is 50 mg/L.

Ships on ice. Store refrigerated at 2 to 8°C 

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Product 6x20 mL $871x20mL $20

Gentamicin Sulfate Solution (10 mg/mL)
400-107

Gentamicin kills Gram-negative and Gram-positive bacteria, and mycoplasma. It works by binding to microbial ribosomes and preventing the initiation of protein synthesis. Recommended dosing in media is 5mL/L.

Sterile-filtered
Ships on ice. Store refrigerated at 2 to 8°C

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Product 6x20 mL $2861x20mL $61

Gentamicin Sulfate Solution (50 mg/mL)
400-108

Gentamicin kills Gram-negative and Gram-positive bacteria, and mycoplasma. It works by binding to microbial ribosomes and preventing the initiation of protein synthesis. Recommended dosing in media is 1 mL/L.

Sterile-filtered
Ships on ice. Store refrigerated at 2 to 8°C

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Product 100 mg $36

Hygromycin B Powder
400-123P

Hygromycin B, an aminoglycoside antibiotic, acts against bacteria, fungi and higher eucaryotes by inhibiting protein synthesis. Originally developed as an antihelminthic, hygromycin B is used in the research laboratory primarily for the selection and maintenance of cells that carry the hygromycin resistance gene.

Ships on ice. Store refrigerated at 2 to 8°C

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Product 20mL $152

Hygromycin B Solution 50mg/mL
400-123

Hygromycin B, an aminoglycoside antibiotic, acts against bacteria, fungi and higher eukaryotes by inhibiting protein synthesis. Originally developed as an antihelminthic, hygromycin B is used in the research laboratory primarily for the selection and maintenance of cells that carry the hygromycin resistance gene.

Ships on ice. Store refrigerated at 2 to 8°C

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IPTG (Isopropyl b-D-thiogalactopyranoside)
400-140P

IPTG is an analog of galactose that is nonmetabolizable and inactivates the lac repressor to induce synthesis of β-galactosidase in E. coli. The expression of cloned genes under the control of the lac operon is induced by IPTG. IPTG is commonly used in cloning procedures that require induction of β-galactosidase and is most often used with X-Gal for blue/white bacterial colony screening.

Store frozen at -20°C

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Product 1 g $185 g $51

Kanamycin Powder
400-114P

Kanamycin, an aminoglycoside antibiotic, acts against bacteria, fungi and higher eukaryotes by inhibiting protein synthesis. Kanamycin is used in the research laboratory primarily for the selection and maintenance of cells that carry the kanamycin resistance gene.

Ships at ambient. Store dry at 15 to 30°C

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Product 5 mg $15310 mg $286

Mitomycin C Powder
400-134P

Mitomycin C is an anti-neoplastic antibiotic, DNA inter-strand, cross-linking alkylating agent that targets guanine nucleoside in the sequence 5 CpG-3 . It produces oxygen radicals and is preferentially toxic to hypoxic cells. It is used to generate mitotically inactive feeder cells used in cell culture systems, such as mitotically inactive fibroblast used in embryonic stem cell (ESC) systems. Soluble in methanol and water.

Ships on ice. Store refrigerated at 2 to 8°C.

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Product 25 g $58100 g $230

Neomycin Sulfate Powder
400-121P

Neomycin Sulfate is an aminoglycoside antibiotic that inhibits translation by binding to the small subunit of prokaryotic ribosomes. Soluble in water. Protect from light and moisture.

Ships at ambient. Store dry at 15 to 30°C

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Product 5g $18525g $625

Paromomycin Sulfate Powder
400-155P

Paromomycin is an aminoglycoside antibiotic isolated from Streptomyces rimosus. It targets a variety of gram-negative and gram-positive bacteria as well as several protozoan species. It displays activity similar to that of neomycin.

Aminoglycoside antibiotics are composed of amino groups attached to glycosides. They bind the 30s ribosomal subunit, causing misreading of the mRNA sequence and inhibition of translocation. Consequently, protein synthesis is inhibited.

Paromomycin sulfate is freely soluble.

Store refrigerated at 2 to 8°C

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Product 25 MU $22100 MU $66

Penicillin G Powder
400-109P

Penicillin G was one of the first and safest antibiotics used in cell culture. It acts by inhibiting bacterial cell wall synthesis. Traditionally it has been used in combination with streptomycin for broader coverage of Gram-negative and Gram-positive bacteria. Recommended concentration is 100 units/mL. Penicillin G has no activity against fungi.

Ships ambient.

Store dry at 15 to 30°C.

 

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