Browse some of the recent publications that have featured our BenchMark™ FBS.

 

The X-linked acrogigantism-associated gene gpr101 is a regulator of early embryonic development and growth in zebrafish

Trivellin, G., Tirosh, A., Hernández-Ramírez, L. C., Gupta, T., Tsai-Morris, C. H., Faucz, F. R., … & Stratakis, C. A. (2020). The X-linked acrogigantism-associated gene gpr101 is a regulator of early embryonic development and growth in zebrafish. Molecular and Cellular Endocrinology, 111091.

 

Luminescence properties and cell uptake analysis of Y2O3: Eu, Bi nanophosphors for bio-imaging applications

Chávez-García, D., Sengar, P., Juarez-Moreno, K., Flores, D. L., Calderón, I., Barrera, J., & Hirata, G. A. (2020). Luminescence properties and cell uptake analysis of Y2O3: Eu, Bi nanophosphors for bio-imaging applications. Journal of Materials Research and Technology.

 

Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution

Wang, Z., Cui, M., Shah, A. M., Tan, W., Liu, N., Bassel-Duby, R., & Olson, E. N. (2020). Cell-Type-Specific Gene Regulatory Networks Underlying Murine Neonatal Heart Regeneration at Single-Cell Resolution. Cell Reports, 33(10), 108472.

 

Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification

Qiu, J., Nordling, S., Vasavada, H. H., Butcher, E. C., & Hirschi, K. K. (2020). Retinoic Acid Promotes Endothelial Cell Cycle Early G1 State to Enable Human Hemogenic Endothelial Cell Specification. Cell Reports, 33(9), 108465.

 

A Novel DNA-Binding Domain in Sterile Alpha Motif Domain-Containing 9 Important for Antiviral Function

Coronado, J. (2020). A Novel DNA-Binding Domain in Sterile Alpha Motif Domain-Containing 9 Important for Antiviral Function (Doctoral dissertation, The University of Texas Health Science Center at San Antonio).

 

Phosphodiesterase 2A and 3B variants are associated with primary aldosteronism​

Rassi-Cruz, M., Maria, A. G., Faucz, F. R., London, E., Vilela, L. A., Santana, L. S., … & Chambô, J. L. (2020). Phosphodiesterase 2A and 3B variants are associated with primary aldosteronism. Endocrine-Related Cancer, 1(aop).

 

Nanotopography Enhances Dynamic Remodeling of Tight Junction Proteins through Cytosolic Liquid Complexes

Huang, X., Shi, X., Hansen, M. E., Setiady, I., Nemeth, C. L., Celli, A., … & Desai, T. A. (2020). Nanotopography Enhances Dynamic Remodeling of Tight Junction Proteins through Cytosolic Liquid Complexes. ACS nano, 14(10), 13192-13202.

 

Protocol for Single-Nucleus Transcriptomics of Diploid and Tetraploid Cardiomyocytes in Murine Hearts

Cui, M., & Olson, E. N. (2020). Protocol for Single-Nucleus Transcriptomics of Diploid and Tetraploid Cardiomyocytes in Murine Hearts. STAR Protocols, 100049.

 

pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise

Reddy, A., Bozi, L. H., Yaghi, O. K., Mills, E. L., Xiao, H., Nicholson, H. E., … & Ferreira, J. C. (2020). pH-Gated Succinate Secretion Regulates Muscle Remodeling in Response to Exercise. Cell, 183(1), 62-75.

 

Disruption of VirB6 paralogs in Anaplasma phagocytophilum attenuates its growth

Crosby, F. L., Munderloh, U. G., Nelson, C. M., Herron, M. J., Lundgren, A. M., Xiao, Y. P., … & Barbet, A. F. (2020). Disruption of VirB6 paralogs in Anaplasma phagocytophilum attenuates its growth. Journal of Bacteriology, 202(23).

 

DNA hypomethylation promotes transposable element expression and activation of immune signaling in renal cell cancer

de Cubas, A. A., Dunker, W., Zaninovich, A., Hongo, R. A., Bhatia, A., Panda, A., … & Rathmell, W. K. (2020). DNA hypomethylation promotes transposable element expression and activation of immune signaling in renal cell cancer. JCI Insight, 5(11).

 

Optical Recordings of Action Potentials and Voltage Sensing Domains

Banks, Q. (2020). Optical Recordings of Action Potentials and Voltage Sensing Domains (Doctoral dissertation).

 

Compressive Stimulation Enhances Ovarian Cancer Proliferation, Invasion, Chemoresistance, and Mechanotransduction via CDC42 in a 3D Bioreactor

Novak, C. M., Horst, E. N., Lin, E., & Mehta, G. (2020). Compressive Stimulation Enhances Ovarian Cancer Proliferation, Invasion, Chemoresistance, and Mechanotransduction via CDC42 in a 3D Bioreactor. Cancers, 12(6), 1521.

 

Fusion of lysosomes to plasma membrane initiates radiation-induced apoptosis

Ferranti, C. S., Cheng, J., Thompson, C., Zhang, J., Rotolo, J. A., Buddaseth, S., … & Kolesnick, R. N. (2020). Fusion of lysosomes to plasma membrane initiates radiation-induced apoptosis. Journal of Cell Biology, 219(4).

 

A Novel Human Skin Tissue Model To Study Varicella-Zoster Virus and Human Cytomegalovirus

Lloyd, M. G., Smith, N. A., Tighe, M., Travis, K. L., Liu, D., Upadhyaya, P. K., … & Moffat, J. F. (2020). A Novel Human Skin Tissue Model To Study Varicella-Zoster Virus and Human Cytomegalovirus. Journal of Virology, 94(22).

 

Examination of clinically-derived p210 BCR/ABL1 RhoGEF mutations in a murine bone marrow transplantation model of CML

Ciccarelli, B. T., Hu, T., Wang, Q., Kim, J. J., & Whitehead, I. P. (2020). Examination of clinically-derived p210 BCR/ABL1 RhoGEF mutations in a murine bone marrow transplantation model of CML. Leukemia Research, 97, 106440.

 

Identification of CD4+ T Cell-Stimulating Plasmodium yoelii Epitopes Via in vivo Immunopeptidomics

VanPelt, M. J. (2020). Identification of CD4+ T Cell-Stimulating Plasmodium yoelii Epitopes Via in vivo Immunopeptidomics (Doctoral dissertation, Drexel University).

 

Visible/Near-Infrared Emitting, Garnet-Based Paramagnetic-Persistent Luminescent Nanocrystals for Two-Photon Bioimaging

Sengar, P., Flores, D. L., Chauhan, K., Can-Uc, B., Juarez-Moreno, K., Contreras, O. E., … & Hirata, G. A. (2020). Visible/Near-Infrared Emitting, Garnet-Based Paramagnetic-Persistent Luminescent Nanocrystals for Two-Photon Bioimaging. Crystal Growth & Design, 20(9), 5880-5889.

 

Co-culture Systems of Drug-Treated Acute Myeloid Leukemia Cells and T Cells for In Vitro and In Vivo Study

Li, Y., Su, R., & Chen, J. (2020). Co-culture Systems of Drug-Treated Acute Myeloid Leukemia Cells and T Cells for In Vitro and In Vivo Study. STAR protocols, 1(2), 100097.

 

Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production

Holani, R., Babbar, A., Blyth, G. A., Lopes, F., Jijon, H., McKay, D. M., … & Cobo, E. R. (2020). Cathelicidin-mediated lipopolysaccharide signaling via intracellular TLR4 in colonic epithelial cells evokes CXCL8 production. Gut microbes, 12(1), 1785802.

 

Processing Human Thymic Tissue for Single Cell RNA-Seq

Le, J., Ha, V. L., Luong, A., & Parekh, C. (2020). Processing Human Thymic Tissue for Single Cell RNA-Seq. STAR protocols, 1(2), 100090.

 

Camouflaged, activatable and therapeutic tandem bionanoreactors for breast cancer theranosis

Chauhan, K., Sengar, P., Juarez-Moreno, K., Hirata, G. A., & Vazquez-Duhalt, R. (2020). Camouflaged, activatable and therapeutic tandem bionanoreactors for breast cancer theranosis. Journal of Colloid and Interface Science, 580, 365-376.

 

A fast, simple, and cost-effective method of expanding patient-derived xenograft mouse models of pancreatic ductal adenocarcinoma

Liu, Z., Ahn, M. H. Y., Kurokawa, T., Ly, A., Zhang, G., Wang, F., … & Liss, A. S. (2020). A fast, simple, and cost-effective method of expanding patient-derived xenograft mouse models of pancreatic ductal adenocarcinoma. Journal of Translational Medicine, 18(1), 1-12.

 

Identification of CD4+ T Cell-Stimulating Plasmodium yoelii Epitopes Via in vivo Immunopeptidomics

VanPelt, M. J. (2020). Identification of CD4+ T Cell-Stimulating Plasmodium yoelii Epitopes Via in vivo Immunopeptidomics (Doctoral dissertation, Drexel University).

 

m 6 A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development

Biancon, G., Nelakanti, R., Lobben, K., Kudo, E., Liu, W., Ardasheva, A., … & Dura, B. (2020). m 6 A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development. Immunity, 52, 1-15.

 

Methodology for in vitro Assessment of Human T Cell Activation and Blockade

Podojil, J. R., Ifergan, I., Chiang, M. Y., Meeks, J. J., & Miller, S. D. (2020). Methodology for in vitro Assessment of Human T Cell Activation and Blockade. Bio-protocol, 10(11), e3644-e3644.

 

Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing

Cui, M., Wang, Z., Chen, K., Shah, A. M., Tan, W., Duan, L., … & Bassel-Duby, R. (2020). Dynamic Transcriptional Responses to Injury of Regenerative and Non-regenerative Cardiomyocytes Revealed by Single-Nucleus RNA Sequencing. Developmental cell.

 

Maintaining immunogenicity of blood stage and sexual stage subunit malaria vaccines when formulated in combination

Parzych, E. M., Miura, K., Long, C. A., & Burns Jr, J. M. (2020). Maintaining immunogenicity of blood stage and sexual stage subunit malaria vaccines when formulated in combination. PloS one, 15(4), e0232355.

 

Electrospun Fibers and Sorbents as a Possible Basis for Effective Composite Wound Dressings

Álvarez-Suárez, A. S., Dastager, S. G., Bogdanchikova, N., Grande, D., Pestryakov, A., García-Ramos, J. C., … & Paz-González, J. A. (2020). Electrospun Fibers and Sorbents as a Possible Basis for Effective Composite Wound Dressings. Micromachines, 11(4), 441.

 

Nanotoxicological study of downconversion Y2O3:Eu3+luminescent nanoparticles functionalized with folic acid for cancer cells bioimaging

Chávez‐García, D., Juarez‐Moreno, K., Calderón‐Osuna, I., Navarro, P., & Hirata, G. A. (2020). Nanotoxicological study of downconversion Y2O3: Eu3+ luminescent nanoparticles functionalized with folic acid for cancer cells bioimaging. Journal of Biomedical Materials Research Part B: Applied Biomaterials.

 

Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics

Durham, N. D., Howard, A. R., Govindan, R., Senjobe, F., Fels, J. M., Diehl, W. E., … & Munro, J. B. (2020). Real-Time Analysis of Individual Ebola Virus Glycoproteins Reveals Pre-Fusion, Entry-Relevant Conformational Dynamics. Viruses, 12(1), 103.

 

A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease

Alexanian, M., Przytycki, P. F., Micheletti, R., Padmanabhan, A., Ye, L., Travers, J. G., … & Linares-Saldana, R. (2020). A Transcriptional Switch Governing Fibroblast Plasticity Underlies Reversibility of Chronic Heart Disease. bioRxiv.

 

β-L-1-[5-(E-2-Bromovinyl)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)] uracil (L-BHDU) effectiveness against varicella-zoster virus and herpes simplex virus type 1 depends on thymidine kinase activity

De, C., Liu, D., Depledge, D., Breuer, J., Singh, U. S., Hartline, C., … & Moffat, J. F. (2020). β-L-1-[5-(E-2-Bromovinyl)-2-(hydroxymethyl)-1, 3-dioxolan-4-yl)] uracil (L-BHDU) effectiveness against varicella-zoster virus and herpes simplex virus type 1 depends on thymidine kinase activity. bioRxiv.

 

β-L-1-[5-(E-2-Bromovinyl)-2-(Hydroxymethyl)-1, 3-Dioxolan-4-yl)] Uracil (L-BHDU) Inhibits Varicella Zoster Virus Replication by Depleting the Cellular dTTP Pool

De, C., Liu, D., Singh, U. S., Chu, C. K., & Moffat, J. F. (2020). β-L-1-[5-(E-2-Bromovinyl)-2-(Hydroxymethyl)-1, 3-Dioxolan-4-yl)] Uracil (L-BHDU) Inhibits Varicella Zoster Virus Replication by Depleting the Cellular dTTP Pool. bioRxiv.

 

Super-resolution visualization of distinct stalled and broken replication fork structures

Whelan, D. R., Lee, W. T. C., Marks, F., Kong, Y. T., Yin, Y., & Rothenberg, E. (2020). Super-resolution visualization of distinct stalled and broken replication fork structures. bioRxiv.

 

Mitochondrial Complex II In Intestinal Epithelial Cells Regulates T-cell Mediated Immunopathology

Fujiwara, H., Mathew, A. V., Kovalneko, I., Pal, A., Lee, H. J., Peltier, D., … & Sun, Y. (2020). Mitochondrial Complex II In Intestinal Epithelial Cells Regulates T-cell Mediated Immunopathology. bioRxiv.

 

A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules

Patel-Murray, N. L., Adam, M., Huynh, N., Wassie, B. T., Milani, P., & Fraenkel, E. (2020). A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules. Scientific reports, 10(1), 1-14.

 

Distinct Roles of Tumor-Associated Mutations in Collective Cell Migration

Lee, R. M., Vitolo, M. I., Losert, W., & Martin, S. S. (2020). Distinct Roles of Tumor-Associated Mutations in Collective Cell Migration. bioRxiv.

 

Fusion of lysosomes to plasma membrane initiates radiation-induced apoptosis

Ferranti, C. S., Cheng, J., Thompson, C., Zhang, J., Rotolo, J. A., Buddaseth, S., … & Kolesnick, R. N. (2020). Fusion of lysosomes to plasma membrane initiates radiation-induced apoptosis. Journal of Cell Biology, 219(4).

 

Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells

Boroughs, L., Ko, B., Sudderth, J., McMillan, E. A., Girard, L., Peyton, M., … & Sekine, I. Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells.

 

Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes

Paul, B. T., Tesfay, L., Winkler, C. R., Torti, F. M., & Torti, S. V. (2019). Sideroflexin 4 affects Fe-S cluster biogenesis, iron metabolism, mitochondrial respiration and heme biosynthetic enzymes. Scientific Reports, 9(1), 1-13.

 

Discovery of small molecules for the reversal of T cell exhaustion

Marro, B. S., Zak, J., Zavareh, R. B., Teijaro, J. R., Lairson, L. L., & Oldstone, M. B. (2019). Discovery of small molecules for the reversal of T cell exhaustion. Cell reports, 29(10), 3293-3302.

 

Proteasome inhibitor-induced modulation reveals the spliceosome as a specific

Huang, H. H., Ferguson, I. D., Thornton, A. M., Lam, C., & Lin, Y. H. T. Proteasome inhibitor-induced modulation reveals the spliceosome as a specific. Biol Chem, 293, 16751-16760.

 

IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression

Elsner, R. A., & Shlomchik, M. J. (2019). IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression. Cell reports, 29(9), 2796-2809.