Human

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Stem Cell Factor (SCF) — Animal Free
300-823P

Human Stem Cell Factor (hSCF) is a growth factor important for the survival, proliferation and differentiation of hematopoietic stem cells and other hematopoietic progenitor cells. This carrier-free product is a recombinant human protein expressed in E. coli.

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

Ships ambient. Store frozen at -20 to -10C.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 10 μg $10550 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Tumor Necrosis Factor alpha (TNF-a) – Animal Free
300-825P

This cytokine is a pro-inflammatory cytokine used to study inflammation conditions. TNF is secreted by macrophages, monocytes, neutrophils, T-cells, NK- cells following their stimulation by bacterial LPS . Cells expressing CD4 secrete TNF-alpha while CD8 cells secrete little or no TNF-alpha. The synthesis of TNF- alpha is induced by many different stimuli including interferons, IL2, GM-CSF. Recombinant Human Tumor Necrosis Factor-alpha produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 158 amino acids and having a molecular mass of 17483.77 Dalton.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Vascular Endothelial Growth Factor-165 (VEGF-165 Animal Free)
300-827P

This growth factor that is very frequently used in many cancer research and atherosclerosis projects. Recombinant Human VEGF is carrier-free and produced in E.Coli. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating vasolidation via nitric oxidedependent pathways. Alternative splicing of the mRNA for VEGF results in several isoforms of the protein being produced.

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Interleukin-10 (IL-10 Animal Free)
300-832P

Interleukin 10 (IL-10) is an anti-inflammatory cytokine mainly produced by macrophages and Th2 cells. IL-10 functions by inhibiting pro-inflammatory cytokines made by macrophages and regulatory T cells including, IFN-γ, TNF-α, IL-2, and IL-3, IL-4, and GM-CSF. IL-10 is also known to suppress antigen presentation on antigen presenting cells. While human IL-10 can act on murine cells, murine IL-10 cannot act on human cells. Recombinant human IL-10 is a non-glycosylated protein, containing 161 amino acids and having a molecular mass of 16.6 kDa.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Interleukin-19 (IL-19 Animal Free)
300-835P

Interleukin-19 (IL-19) is a member of the IL-10 family produced by resting B cells and monocytes, being up-regulated when monocytes are treated with GM-CSF or LPS. IL-19 shares a receptor complex with IL-20, and functional acts to induce IL-6 and TNF-α production by monocytes and promotes the Th2 response. Recombinant human IL-19 is a non-glycosylated protein, containing 155 amino acids and having a molecular mass of 17.9 kDa.

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 5 μg $10520 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Epstein-Barr Virus Induced Gene 3 (EBI3) – Animal Free
300-836P

Epstein-Barr Virus Induced Gene-3 (EBI3), is a secreted glycoprotein belonging to the hematopoietin receptor family and is related to the p40 subunit of IL-12. EBI3 was identified by its induced expression in B-lymphocytes in response to Epstein-Barr virus infection. EBI3 forms heterodimers with p28 to form IL-27 and with p35 to form IL-35. Both IL-27 and IL-35 have anti-inflammatory and regulatory activity. Recombinant human EBI3 is a non-glycosylated protein, containing 209 amino acids, with a molecular weight of 23.3 kDa.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 5 μg $10520 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Leukemia Inhibitory Factor (LIF Animal Free)
300-837P

Human Leukemia Inhibitory Factor (LIF) is member of the IL-6 family and is made by a variety of tissues. Human LIF signals through gp130 to activiate STAT3 in human ESCs . In mouse ESCs, LIF promotes self-renewal and pluripotentcy, but in human cells there is no indication that LIF has the same function. Instead, FGF-basic (FGF-2) and Activin A are used to promote self-renewal and pluripotent potential.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Vascular Endothelial Growth Factor-121 (VEGF-121 Animal Free)
300-840P

Vascular Endothelial Growth Factor-A (VEGF-A) was originally isolated from tumor cells and is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability, VEGF-A may play a role in stimulating vasodilatation via nitric oxide-dependent pathways. VEGF-A has several variants, one being VEGF-121. Rat and bovine VEGF are one amino acid shorter than the human factor, and the bovine and human sequences show a homology of 95%.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Macrophage Colony-Stimulating Factor (M-CSF Animal Free)
300-842P

Macrophage colony stimulating factor (M-CSF) is a hematopoietic growth factor produced by a wide variety of cells. M-CSF is known to stimulate differentiation of hematopoietic stem cells to monocyte-macrophagecell populations in culture. M-CSF acts through the CSF receptor 1. Although human M-CSF shows activity on mouse cells, mouse CSF shows no activity on human cells. Recombinant human M-CSF is a disulfide linked homodimer, containing two 159 amino acids and having a total molecular mass of 36.8kDa.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Omentin (Animal Free)
300-843P

Omentin is a member of the adipokine family of cytokines typically made and secreted by adipose tissue that surrounds internal organs and also by the small intestine.  Omentin enhances insulin-stimulated glucose uptake in adipocytes and is considered to be a link between obesity and Type 2 Diabetes.  Recombinant human Omentin is a non-glycosylated protein, containing 313 amino acids, with a total molecular weight of 35 kDa.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 5 μg $10520 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Pleiotrophin (PTN Animal Free)
300-844P

Pleiotrophin, or PTN, is a growth factor that has mitogenic effects on fibroblast, epithelial, and endothelial cells as well as induces neurite outgrowth.  PTN is made by many tissues, but predominantly by the tissues of the nervous system during development.  PTN shows a high affinity for heparin.  Recombinant human PTN is a non-glycosylated protein, containing 137 amino acids, with a molecular weight of 15.4 kDa.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 5 μg $10525 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Fibroblast Growth Factor-10 (FGF-10 / KGF-2) – Animal Free
300-851P

Fibroblast Growth Factor 10 (FGF-10) is a growth factor involved in a broad range of functions that include morphogenesis, proliferation, embryonic development, tissue repair and more. 

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

Ships ambient. Store frozen at -20 to -10C.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 10 μg $10550 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Heparin Binding EGF-like Growth Factor (HB-EGF) – Animal Free
300-853P

Heparin Binding EGF-like Growth Factor (HB-EGF) is a growth factor expressed by monocytesand macrophages.  HB-EGF mediates its effects via EGFR, ERBB2 and ERBB4 and has higher binding affinity to the EGFR than EGF itself.  It is a mitogen for fibroblasts and smooth muscle cells, but not endothelial cells. 

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

Ships ambient. Store frozen at -20 to -10C.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Oncostatin M (OSM) – Animal Free
300-857P

Oncostatin M (OSM) is a growth regulator produced by a variety of cells and has a wide range of attributed functions.  Several of these functions include: inhibition of tumor cell line proliferation, liver development/regeneration, regulation of cytokine production (hematopoiesis and inflammation), bone development and possibly nervous system development. 

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

Ships ambient. Store frozen at -20 to -10C.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 5 μg $10520 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Persephin (PSP) – Animal Free
300-860P

Persephin (PSP) is a neurotrophic factor that promotes survival and growth of dopaminergic and motor neurons, but not peripheral neurons. 

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

Ships ambient. Store frozen at -20 to -10C.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Fibroblast Growth Factor-7 (FGF-7 / KGF) – Animal Free
300-861P

Fibroblast Growth Factor 7 (FGF-7) is a growth factor predominantly expressed during embryonic development, playing a key role in limb development.  In culture, FGF-7 might be important for epithelial cell proliferation.

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

Ships ambient. Store frozen at -20 to -10C.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Granulocyte Colony Stimulating Factor (G-CSF) – Animal Free
300-862P

Granulocyte Colony-Stimulating Factor, or G-CSF, is a growth factor that is considered the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, IL-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF, while in epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by IL-17.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Glial Derived Neurotrophic Factor (GDNF) – Animal Free
300-863P

Glial Cell Line-Derived Neurotrophic Factor, or GDNF, is a neurotrophic factor that is closely related to other neurotrophic factors such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes receptors known as RET, and GFRα1-4 to promote dopamine uptake, survival and differentiation of neurons. Recombinant human GDNF is a non-glycosylated homodimer, containing two 135 amino acid proteins and has a total molecular mass of 30.4 kDa.

*Single-unit price. For inquiries about this product, contact your sales representative.

Product 2 μg $10510 μg $244100 μg Inquire500 μg Inquire1 Mg Inquire

Human Interleukin-5 (IL-5) Animal Free
300-864P

Interleukin-5 (IL-5) is a hematopoietic growth factor expressed in Th2, mast cells and eosinophils.  IL-5 acts through its receptor, the IL-5 receptor (IL-5R) and is involved in B cell growth and eosinophil activation.  Human and mouse IL-5 are cross-reactive. 

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

Ships ambient. Store frozen at -20 to -10C.

*Single-unit price. For inquiries about this product, contact your sales representative.