Macrophage Inflammatory Protein-3 alpha (MIP-3α), also called
CCL20, is expressed in the liver, lungs, lymph nodes and
peripheral blood lymphocytes. MIP-3α is strongly up regulated by
inflammatory signals, and down regulated by the anti-inflammatory
cytokine IL-10. MIP3α signals through the G protein-coupled
receptor, CCR6, and acts as a chemoattractant to lymphocytes and
dendritic cells. Recombinant human MIP-3 alpha is a
non-glycosylated protein, consisting of 70 amino acids and has a
molecular mass of 8.0 kDa.
Ships ambient. Store frozen at -20 to -10C.
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