Mouse

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Mouse Macrophage Inflammatory Protein-3 beta (MIP-3 β / CCL19)
300-335P

Macrophage Inflammatory Protein-3 beta (MIP-3β), also called CCL19, is a chemokine that is expressed in the thymus, lymph nodes and activated bone marrow stromal cells. MIP-3β signals through the G protein-coupled receptor, CCR7, to regulate normal lymphocyte recirculation and homing of T and B cells to the lymph nodes. Human MIP-3β shows activity on mouse cells. Recombinant mouse MIP-3beta is a non-glycosylated protein, consisting of 83 amino acids, with a molecular weight of 9.2 kDa.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Migration Inhibitory Factor (MIF)
300-371P

Macrophage Migration Inhibitory Factor (MIF) is a pro-inflammatory cytokine that acts by inducing IL-1, IL-8 and MMP expression. MIF stimulates NO production and TNF-α release following IFNγ-activation of macrophages. 

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Mouse Migration Inhibitory Factor (MIF) – Animal Free
300-870P

Macrophage Migration Inhibitory Factor (MIF) is a pro-inflammatory cytokine that acts by inducing IL-1, IL-8 and MMP expression. MIF stimulates NO production and TNF-α release following IFNγ-activation of macrophages. 

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Monocyte Chemotactic Protein-1 (MCP-1 / CCL2)
300-336P

Monocyte Chemotactic Protein 1 (MCP-1), also known as CCL2, is thought to be produced by injured or infected tissues. MCP-1 signals through G protein-coupled receptors, CCR2 and CCR4, to recruit memory T cells, monocytes and dendritic cells. Recombinant mouse MCP-1 is a non-glycosylated protein, containing 125 amino acids, with a molecular weight of 13.8 kDa.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Monocyte Chemotactic Protein-2 (MCP-2 / CCL8)
300-337P

Monocyte Chemoattractant Protien 2 (MCP-2), also known as CCL8, is implicated in allergic responses through its ability to activate mast cells, eosinophils, and basophils. MCP-2 is known to signal through several G protein-coupled receptors including, CCR1, CCR2B, and CCR5. Recombinant mouse MCP-2 is a non-glycosylated protein, containing 74 amino acids and having a molecular mass of 8.5 kDa.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Monocyte Chemotactic Protein-3 (MCP-3 / CCL7)
300-338P

Monocyte Chemoattractant Protein 3 (MCP-3), also called CCL7, is produced by macrophages and some tumor cell lines. MCP-3 signals through three different G protein-coupled receptors, CCR1, CCR2, and CCR3. CCL7 chemoattracts monocytes and can regulate macrophage function. Recombinant mouse MCP-3 is a non-glycosylated protein, containing 74 amino acids and having a molecular mass of 8.5 kDa.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Nerve Growth Factor beta (NGF-β)
300-339P

Nerve Growth Factor (NGF-β) is a neurotrophic factor related to BDNF, NT-3 and NT-4. NGF-β acts through its receptor β-NGFR, and is involved in the development and maintenance of the sensory and sympathetic nervous systems. NGF-β also is also involved in the growth, differentiation and survival of B lymphocytes. Human, mouse and rat proteins show cross-reactivity. Recombinant mouse NGF-beta is a non-glycosylated, non-covalently linked homodimer, containing  two 120 amino acid proteins and having a molecular mass of 13. 5 kDa each.

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Mouse Platelet Derived Growth Factor AA (PDGF AA)
300-341P

Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-α, TGF-β and EGF. Recombinant mouse PDGF-AA is a non-gylcosylated disulfide-linked homodimer. It is comprised of two 126 amino acid proteins, each with a total molecular weight of 28.9 kDa.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Platelet Derived Growth Factor BB (PDGF BB)
300-342P

Platelet-Derived Growth Factor (PDGF) is a mitogenic peptide growth hormone carried in the alpha-granules of platelets and is released when platelets adhere to traumatized tissues. Connective tissue cells near the traumatized region respond by initiating the process of replication. The synthesis of PDGF can be induced by IL-1, IL-6, TNF-α, TGF-β and EGF. Recombinant mouse PDGF-BB is a non-glycosylated, disulfide-linked homodimer, consisting of two PDGF-B chains of 109 amino acids each. The final dimer has a total molecular weight of 24.6 kDa.

Ships ambient.

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Mouse RELM alpha (RELM-α)
300-344P

Resistin-like alpha, or RELM-α, is a cytokine member to a unique family of proteins including Relm-β and Resistin. Relm-α and Resistin are secreted by adipocytes, where as Relm-β is secreted by intestinal epithelial cells. All members of the family share a high conserved C-terminal region with 10 Cysteine residues. Recombinant mouse RELM-alpha is a non-glycosylated protein, containing 88 amino acids with a molecular weight of  10 kDa.

Ships ambient. Store frozen at -20 to -10C.

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Mouse RELM beta (RELM-β)
300-345P

Resistin-Like Molecule-beta (RELM- β) is a member of a recently identified family of secreted proteins containing conserved cysteines in their C terminus. The RELM family consists of Resistin (also called FIZZ3), RELM-α (FIZZ1), and RELM-γ. Only Resistin and RELM-β were found in humans whereas all four RELM family members have been identified in rodents.Recombinant mouse RELM-beta is a non-glycosylated protein, consisting of 83 amino acids, with a molecular weight of 8.9 kDa.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Resistin Dimer
300-362P

Resistin is a peptide hormone belonging to the class of cysteine-rich secreted proteins which is termed the RELM family and is also described as ADSF (Adipose Tissue-Specific Secretory Factor) and FIZZ3 (Found in Inflammatory Zone). Mouse resistin is produced by adipocytes and may be an important link between obesity and insulin resistance. Recombinant mouse resistin is a non-glycosylated, disulfide-linked homodimer, containing two identical 95 amino acid chains, with a total molecular weight of 20.6 kDa.

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Mouse Soluble RANK Ligand
300-346P

Receptor Activator of NF-kappa B Ligand (RANKL) is a cell-bound marker (CD254) related to the TNF family of proteins. RANKL plays a critical role in bone metabolism, particularly osteoclast differentiation. In addition, RANKL is expressed by some T cells is thought to promote dendritic cell maturation. Recombinant mouse soluble RANK Ligand is a non-glycosylated protein, containing 174 amino acids and having a molecular weight of 19.9 kDa.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Soluble RANK Ligand – Animal Free
300-871P

Receptor Activator of NF-kappa B Ligand (RANKL) is a cell-bound marker (CD254) related to the TNF family of proteins. RANKL plays a critical role in bone metabolism, particularly osteoclast differentiation. In addition, RANKL is expressed by some T cells is thought to promote dendritic cell maturation. Recombinant mouse soluble RANK Ligand is a non-glycosylated protein, containing 174 amino acids and having a molecular weight of 19.9 kDa.

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

*Single-unit price. For inquiries about this product, contact your sales representative.

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Mouse Sonic Hedgehog (SHH)
300-347P

Sonic hedgehog (SHH) is a member of a small group of secreted proteins that are essential for development in both vertebrates and invertebrates. Three mammalian hedgehog genes (sonic, desert, Indian) share about 60% homology and all signal via the same receptors.  Recombinant mouse SHH is a non-glycosylated protein, consisting of 176 amino acids, with a molecular weight of 19.8 kDa. The Cys at position 25 has been substituted with Ile.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Stem Cell Factor (SCF)
300-348P

Mouse Stem Cell Factor is involved in the survival, differentiation, and activation of myeloid, erythroid, lymphoid, mast cells, eosinophils and other progenitor cells. SCF signals through its receptor, tyrosine kinase SCF R/c-kit. This carrier-free product is a recombinant mouse protein expressed in E. coli.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Stromal Cell-Derived Factor-1 alpha (SDF-1 α / CXCL12)
300-349P

Stromal Cell Derived Factor-1 alpha (SDF-1α), also called CXCL12, is one of two splice variants made by a wide variety of cells when stimulated by inflammatory cytokines such as, TNF, IL-1 or LPS. SDF-1α signals through the G protein-couple receptor, CXCR4, to recruit activated leukocytes. Human and mouse SDF-1α share 99% sequence identity. Recombinant mouse SDF-1 alpha is a non-glycosylated protein, containing 68 amino acids and having a molecular mass of 7.9 kDa.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Stromal Cell-Derived Factor-1 beta (SDF-1β / CXCL12)
300-350P

Stromal Derived Growth Factor-1β (SDF-1β), also called CXCL12, is one of two splice variants made by a wide variety of cells when stimulated by inflammatory cytokines such as, TNF, IL-1 or LPS. SDF-1β signals through the G protein-couple receptor, CXCR4, to recruit activated leukocytes. Human SDF-1β shares 100% identity to feline SDF-1β.  Recombinant mouse SDF-1β is a non-glycosylated protein, comprised of 72 amino acids with a molecular weight of 8.5 kDa.

Ships ambient. Store frozen at -20 to -10C.

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Mouse Thrombopoietin (TPO Animal Free)
300-848P

Thrombopoietin (TPO) is a growth factor that is produced by the liver and kidney. TPO acts through theTPO receptor to promote megakaryocyte maturation and differentiation, which leads to the production of platelets.  Recombinant mouse TPO is a non-glycosylated protein, containing 174 amino acids (which comprise the receptor binding domain), having a molecular mass of 18.7 kDa.  

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Mouse Thrombopoietin (TPO)
300-351P

Thrombopoietin (TPO) is a growth factor that is produced by the liver and kidney. TPO acts through the TPO receptor to promote megakaryocyte maturation and differentiation, which leads to the production of platelets.  Recombinant mouse TPO is a non-glycosylated protein, containing 174 amino acids (which comprise the receptor binding domain), having a molecular mass of 18.7 kDa.

Ships ambient. Store frozen at -20 to -10C.

*Single-unit price. For inquiries about this product, contact your sales representative.