Equine Platelet Derived Growth Factor-BB – Animal Free
300-947P

Product 5 μg $10920 μg $253100 μg inquire500 μg inquire1 Mg inquire

Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis.  PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling.  PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.  PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues.  PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB).  The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β. 

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

Ships ambient. Store frozen at -20 to -10°C

*Single-unit price. For inquiries about this product, contact your sales representative.