Equine Platelet Derived Growth Factor-BB (PDGF-BB)
300-712P

Product 5 μg $9920 μg $229100 μg inquire500 μg inquire1 Mg inquire

 Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis.  PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling.  PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.  PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues.  PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB).  The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β. 

Ships ambient. Store frozen at -20 to -10°C

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