Human Epstein-Barr Virus Induced Gene-3 (EBI-3)
Epstein-Barr Virus Induced Gene-3 (EBI3), is a secreted glycoprotein belonging to the hematopoietin receptor family and is related to the p40 subunit of IL-12. EBI3 was identified by its induced expression in B-lymphocytes in response to Epstein-Barr virus infection. EBI3 forms heterodimers with p28 to form IL-27 and with p35 to form IL-35. Both IL-27 and IL-35 have anti-inflammatory and regulatory activity. Recombinant human EBI3 is a non-glycosylated protein, containing 209 amino acids, with a molecular weight of 23.3 kDa.
Ships ambient. Store frozen at -20 to -10C.
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