Human Glial Derived Neurotrophic Factor (GDNF)
Glial Cell Line-Derived Neurotrophic Factor, or GDNF, is a neurotrophic factor that is closely related to other neurotrophic factors such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes receptors known as RET, and GFRα1-4 to promote dopamine uptake, survival and differentiation of neurons. Recombinant human GDNF is a non-glycosylated homodimer, containing two 135 amino acid proteins and has a total molecular mass of 30.4 kDa.
Store frozen at -20 to -10C.
*Single-unit price. For inquiries about this product, contact your sales representative.