Human Leukemia Inhibitory Factor (LIF)
Human Leukemia Inhibitory Factor (LIF) is member of the IL-6 family and is made by a variety of tissues. Human LIF signals through gp130 to activiate STAT3 in human ESCs . In mouse ESCs, LIF promotes self-renewal and pluripotentcy, but in human cells there is no indication that LIF has the same function. Instead, FGF-basic (FGF-2) and Activin A are used to promote self-renewal and pluripotent potential. Recombinant human LIF is a non-glycosylated protein, containing 181 amino acids, with a molecular weight of 19.9 kDa.
Ships ambient. Store frozen at -20 to -10C.
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