Human TARC (CCL17)

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Thymus and activation regulated chemokine (TARC), also known as CCL17, is a chemokine produced by thymus tissue constitutively and activated PBMCs (mainly DCs). TARC signals through the CCR4 receptor to induce chemotaxis of Th2 cells. TARC is thought to be important in asthma and allergic diseases, along with bacterial and viral infections. Recombinant human TARC is a non-glycosylated protein, containing 71 amino acids, with a molecular weight of 8.1 kDa.

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