Human Transforming Growth Factor-alpha (TGF-α) – Animal Free
300-892P

Product 20 μg $98100 μg $228250 μg Inquire500 μg Inquire1Mg Inquire

Tumor growth factor alpha (TGF-α) is a member of the epidermal growth factor (EGF) family. TGF-α function is mediated through binding the EGF receptor (EGFR) to activate receptor tyrosine kinase signaling.  TGF-α functions as a mitogen to activate epithelial cell proliferation, growth, and differentiation.  In the gastric mucosa, TGF-α production inhibits gastric acid secretion and therefore plays a central role in the pathogenesis of the stomach syndrome Ménétrier’s disease.  TGF-α is also produced in adult macrophages, brain cells, keratinocytes, and is widely expressed in cancer cells. 

This product is produced using Animal Free raw components and processes, in a non-mammalian system.

Ships ambient. Store frozen at -20 to -10C.

*Single-unit price. For inquiries about this product, contact your sales representative.