Human Tumor Necrosis Factor Receptor Type 1 (TNF-Receptor-1)
TNF Receptor 1 (TNFR1) is expressed in most tissues and is activated by soluble an membrane-bound TNF-alpha. TNFR1 is known to activate NF-kappaB and MAPK pathway s and functions to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis and inhibit viral replication. The soluble from of human recombinant TNFR1 is a non-glycosylated protein, containing 192 amino acids and having a molecular mass of 20.9 kDa.
Ships ambient. Store frozen at -20 to -10C.
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