Mouse Interleukin-17F Heterodimer (IL-17F Heterodimer)
300-318P

Product 5 µg $9025 µg $207100 µg Inquire500 µg Inquire1 Mg Inquire

Interleukin-17AF (IL-17AF) is a member of the IL-17 family of proteins produced by a subset of T cells, called Th17, following stimulation with IL-23. Since IL-17AF is thought to signal through the IL-17R receptor, its biological function is similar to that of IL-17A in that it induces the production of a variety of chemokines, in addition to airway neutrophilia. In regard to these functions, IL-17AF has less activity than the IL-17A homodimer but, greater activity than the IL-17F homodimer. Human and rat IL-17AF both show activity on mouse cells.Recombinant mouse IL-17AF is a non-glycosylated, disulfide-linked heterodimer. It is comprised of one monomeric subunit each of IL-17A and IL-17F, having a total of 271 amino  acids and an molecular weight of 30.7 kDa.

Ships ambient. Store frozen at -20 to -10C.

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