Mouse Vascular Endothelial Growth Factor-165 (VEGF-165)

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Vascular Endothelial Growth Factor-A (VEGF-A) was originally isolated from tumor cells and is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability, VEGF-A may play a role in stimulating vasodilatation via nitric oxide-dependent pathways. VEGF-A has several variants, VEGF-165 being the most abundant.

Rat and bovine VEGF are one amino acid shorter than the human factor, and the bovine and human sequences show a homology of 95%.Recombinant mouse VEGF-165 is a non-glycosylated, disulfide-linked homodimer, containing 165 amino acids and having a molecular mass of 39 kDa.


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