Case study: Uniquely allowing large fold expansion of adherent cells with no passaging in a GMP compliant bioreactor system
Webinar
We present anonymized data from an ongoing collaboration that
demonstrates our ability to eliminate passaging (cell harvest and
reseeding) and go from small cell numbers (<1 million) to
clinically relevant numbers (as high as 2 billion) in one closed
device with simple to use microcarriers. We show how our
microcarrier-based culture offers an effective solution to
process scale up in our closed system.
The capability to take full samples (cells, not just medium)
allows users to do quality checks on their cell product at any
point in the culture cycle to ensure the process is working. This
system allows full visibility into process monitoring and control
options (pH, oxygen, temperature, and biomass). It also saves
users costs for cell therapy production by significantly reducing
the involved labor, consumable use, and cleanroom
requirements. Learn more about how the Scinus
Bioreactor can achieve a clinically relevant number of
cells.